Toronto Blue Jays vs Kansas City Royals Prediction, Odds and Picks for Today, 09/20/25

The Blue Jays have been one of the best teams in baseball in the second half of the season, but they enter Saturday’s matchup against the Royals in a skid. Toronto has dropped 3 games in a row, and lost last night’s game by a score of 20-1. The offense has gone cold, scoring just 2 total runs over the 3-game losing streak. Things won’t get any easier as they are set to go up against Kansas City left-hander Noah Cameron in this one. Cameron owns a strong 2.98 ERA and 1.09 WHIP through 22 starts so far in his rookie season. He is holding opponents to a .217 batting average at home, and should be able to keep the Blue Jays at bay.

Shane Bieber is making just his sixth start of the season. He’s been solid, but in 2 road starts he’s allowed 6 earned runs over 12 innings of work. Kansas City’s offense appears to be in a groove right now and should be able to give Bieber some problems. Normally, fans and bettors can expect a spirited effort from a team that just got blown out the night before. But in this case, the juice may not be worth the squeeze when considering backing the Blue Jays. Make it a small play, but consider backing the Royals on the run line +1.5 at home.

Blue Jays vs Royals prediction: Royals +1.5 (-130) available at time of publishing. Playable at that number.

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