Toronto Blue Jays vs New York Yankees Prediction, Odds and Picks for Today, 09/05/25

The Blue Jays and Yankees are set to begin a 3-game series at Yankee Stadium on Friday night. Kevin Gausman will take the mound for Toronto, and he is in desperate need of some run support. Since scoring 20 runs in Gausman’s start against the Rockies on August 6, the Blue Jays have scored just 7 total runs in Gausman’s last 4 starts. The veteran right-hander has pitched well in those games, allowing just 19 hits in 25 innings over the span. The Blue Jay offense has exploded over their last 2 games, scoring 25 runs in their last 2 games against the Reds. Now is the time for them to start backing Gausman up.

New York’s Cam Schlitter has been outstanding over his 9 starts this season. The rookie right-hander owns an impressive 2.61 ERA and 1.24 WHIP over 48.1 innings of work. However, he is still a young pitcher, and Toronto has a veteran lineup that is rolling right now. Plus, Schlitter hasn’t been nearly as strong when pitching at Yankee Stadium. He owns a 3.16 ERA and .253 BAA in home home ballpark, compared to a 1.99 ERA and .195 BAA when pitching on the road. Consider backing the Blue Jays on the road against the rookie pitcher.

Blue Jays vs Yankees prediction: Blue Jays ML (+110) available at time of publishing. Playable at that number.