Toronto Blue Jays vs Tampa Bay Rays Prediction, Odds and Picks for Today, 09/17/25

The Blue Jays have taken the first 2 games of this series by scores of 2-1 and 6-5. They now enter Wednesday’s matchup riding a riding a 6-game win streak. The Blue Jays have been one of the best teams in baseball since the All-Star break, and with the way they are rolling, it’s tough to go against them right now. It also helps that Kevin Gausman is slated to take the mound for Toronto. Gausman is coming off a complete game, 2-hit shutout against the Astros, and has allowed just 2 earned runs over his last 3 starts and 24 innings of work. Pitching on the road hasn’t phased him, as he is holding opponents to a measly .190 batting average away from Toronto. Look for the veteran right-hander to stay locked in against the Rays in this one.

The Rays appear to just be trying to get to the finish line at this point. Tampa Bay has fallen to 9 games back in the wild card, and has lost 9 of their last 11 games. Ian Seymour has been solid since transitioning to a starting role, but he has a tough assignment in this one going up against a Toronto offense that is doing plenty of damage right now. Back the Blue Jays on the road.

Blue Jays vs Rays prediction: Blue Jays ML (-130) available at time of publishing. Playable to -135.