Washington Nationals vs Atlanta Braves Prediction, Odds and Picks for Today, 09/22/25

There are only 3 games on the MLB slate on Monday, including the Washington Nationals vs the Atlanta Braves. This game has no meaning, so it is not a spot we want to get too heavily invested in. The Braves are closing the season on a tear though, for what it is worth, having now won 8 in a row, including an absolutely devastating sweep of the Detroit Tigers over the weekend. Earlier in the week, the Braves also took 4 from the Nats, and that by a combined score of 31-10. The Money Line is juiced up way too high to mess with, so I think the right play in this game is the Braves on the Run Line.

Chris Sale takes the mound for Atlanta. He hurled 8 scoreless innings against the Nationals a few days ago, so I am not super interested in betting against him on Monday. The Nats will go with MacKenzie Gore. Gore tossed 5 scoreless against the Braves last week, but the Nats are handling him with care and limiting his pitch count since he is only making his 3^rd start since returning from the IL. In short, this week does not matter for Gore; next season does. I expect the Nats to get him out of there early, and then it goes to the bullpen, and I am always standing in line to fade this Nationals’ bullpen. I think Atlanta pulls away again.

Nationals vs Braves Prediction: Braves -1.5 (-110) available at the time of publishing. Playable at that number.