Washington Nationals vs Cincinnati Reds Prediction, Odds and Picks for Friday, 05/02/25

The Washington Nationals head to Cincinnati to take on the Reds in a Friday night matchup at Great American Ball Park. Hunter Greene is slated to take the mound for the Reds, and he will be happy to be back at home. After allowing just 3 earned runs and 1 home run in his first 4 starts of the season, Greene allowed 8 earned runs and 5 home runs over his last 2 outings at Baltimore and at Colorado. In 3 home starts this season, the hard-throwing right-hander owns a solid 1.42 ERA and opponents are hitting just .123 against him. Greene could be in a solid bounce back spot here, as the Nationals are in the middle of a 6-game road trip, and their team OPS drops from .773 at home to .613 on the road.

On the other side, Mitchell Parker will be the starter on the bump for Washington. Parker has been solid so far this season, but he has just 20 strikeouts in 37.1 innings of work. He tends to pitch to contact, which might not be the best strategy at hitter-friendly Great American Ball Park. Greene has the ability to overpower Washington’s lineup, while Parker might have trouble doing the same. Roll with the Reds.

Nationals vs Reds prediction: Reds ML (-170) available at time of publishing. Playable to -180.

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