Chicago Bulls vs Portland Trail Blazers Prediction, Odds and Picks for Today, 11/19/25

The Chicago Bulls wrap up a four-game road trip in the Pacific Northwest against the Portland Trail Blazers. The Bulls picked up a stunning 130-127 victory in Denver as a 12.5-point underdog as the Over (241) cashed, snapping a five-game losing streak. The Bulls are still 3-2 against the spread (ATS) in the past five games, and the Over has cashed in five in a row, including four straight Over results on the road. Be careful if you’re looking for a same-game parlay (SGP), though, as the general public loves the Bulls, and Chicago is just 2-4 ATS in the past six road contests.

For the Blazers, they suffered a 127-110 loss at home against the Phoenix Suns on Tuesday night, and now they face the quick turnaround. At least the Blazers are back home, so playing back-to-back situations is better when you do not have to travel. Playing on no rest this season, Portland won and covered its only previous game on no rest, topping the Lakers 122-108 in Los Angeles on Oct. 27, and it cashed the Over in that game on no rest. Rather than bothering with the side, which a majority of the money is on Chicago, let’s take the Over here, even though it’s a big number. That’s the safer play, cashing in seven of the past eight games for Portland.

Over 243.5 (-110) at time of publishing. Playable to 244.5.