Detroit Pistons vs Los Angeles Clippers Prediction, Odds and Picks for Today, 12/28/25

The Los Angeles Clippers have picked up 3-straigh wins largely due to improved defensive performances, holding 3 straight opponents to below 110 points. They should have issues keeping that streak going tonight up against the Detroit Pistons. Over the last 10 games the visitors are 6th in the league in offensive rating and have managed at least 110 in 9 straight games, including surpassing 130 points in each of their last 2 contests. Ivica Zubac continues to be unavailable for the hosts, meaning Brook Lopez will draw the start once more. The Pistons have an elite playmaker in Cade Cunningham that should be well positioned to go at the slow-footed center in pick and roll situations. Lopez does however provide great scoring potential, as witnessed by his 9 made 3-pointers in his last game.

The Pistons do prefer to play at a higher tempo, taking any opportunity they can to get out in transition. In fact, over the last 10 games, they lead the league in fast break points per game. Against a team in the bottom half of the league in points allowed in that category, it should be a point of emphasis for them here. Outside of Ausar Thompson, the Pistons lack lock down defenders in their starting 5. That was evident in their last outing where they gave up 30-point games to both Lauri Markannen and Keyonte George. With Lopez spreading the floor and creating space, look for James Harden and Kawhi Leonard to be able to take advantage of this and help the Clippers do their part for the over.

Detroit Pistons vs Los Angeles Clippers prediction: Over 224.5 (-110) available at time of publishing. Playable to 226.

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