Indiana Pacers

Indiana Pacers vs Cleveland Cavaliers Prediction, Odds and Game 2 Picks for Today, 05/06/25

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Pacers
1-0
Pacers
Today
Cavaliers
0-1
Cavaliers

Vote on who will cover the spread!

Cleveland Cavaliers

Pacers vs Cavaliers Pickswise Expert Predictions

Indiana Pacers
NBA
Cleveland Cavaliers
Point Spread Pick
IND Pacers +9.0(-110)IND Pacers @ CLE Cavaliers

The Cleveland Cavaliers could be in trouble in this series. Not only did they drop Game 1, but they also enter tonight’s home game against the Indiana Pacers with issues affecting key personnel. Darius Garland remains questionable after missing their first game and is joined by Evan Mobley and De’Andre Hunter with the same injury designation. If a couple of these key players are unable to take to the floor, it could present the visitors with a fantastic opportunity to take a 2-0 lead back to Indiana. Even if they can suit up, their injuries could really impact their performance levels. It would leave Donovan Mitchell to carry the offense. And while he attempted this in his last outing, as forked up 30 shots, he was only able to knock down 43.3% of those. With strong perimeter defenders like Aaron Nesmith on him and Myles Turner waiting for him in the paint, it will be tough for Mitchell to improve without the help of his supporting cast.

If Mobley cannot play or is slowed down by his ankle injury, it could help unlock Pascal Siakam for the Pacers. Siakam is one of the best power forwards in the NBA off the dribble and should be able to really test Cleveland’s defensive star. If the home team needs to send help his way, the Pacers should be able to punish them; they currently lead all teams in 3-point percentage. Considering that in the series opener the Pacers knocked down 10 more shots from beyond the arc than their opponents, the Cavaliers may have real issues overturning that outcome if they cannot close that gap in makes. Getting 9 points with the Pacers given all of Cleveland’s questions looks too good to pass up.

Pacers vs Cavaliers prediction: Indiana +9 (-110) available at time of publishing. Playable to +8.

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Germantas Kneita
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Germantas Kneita

Like most Lithuanians, I started watching basketball from the age of six. I'm based out in London and played basketball at the University of Lincoln here in the UK. I had always had an interest in the NBA but things really took off in the summer of 2010. That year Linas Kleiza led Lithuania to 3rd place at the World Championships and signed with the Toronto Raptors to replace the departing Chris Bosh. I've been a Raptors fan since that day and I've not missed a game since. I've been handicapping games for more than a decade, specializing in player props. For Germantas Kneita media enquiries, please email contact@pickswise.com.
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Same Game Parlay

Player Assists
D. Garland (CLE) - Over 5.5 assists
Player Threes Made
D. Hunter (CLE) - Over 1.5 threes
Player Rebounds
A. Nesmith (IND) - Over 4.5 rebs

Darius Garland to record 6+ assists (-130)

Going down 1-0 is not the time to hit the panic button, but if the Cavaliers fail to win Game 2 they are in trouble. For them to avoid doing that, they’ll have to bring back Darius Garland, who has been out for a while with a toe injury. Facing the Miami Heat without him didn’t make much of a difference, but his absence was clearly felt in Game 1 of this series as the Cavaliers finished with 25 assists, down from the 28 they averaged during the regular season.

Apart from the raw numbers, Garland’s presence should have a massive impact on the gameplan of the Pacers, who will have to adjust their defensive coverages as he draws so much attention being the team’s main playmaker. Over his last 10 games, Garland has averaged 7.4 assists per game, clearing this line a total of 8 times. In Game 2 of the Miami series he had 9 dimes. The Cavaliers need Garland big-time here and hopefully he steps up.

De’Andre Hunter 2+ made threes (-156)

One of the players who should benefit greatly from Garland’s playmaking is De’Andre Hunter. He didn’t have the best of games in the series opener, finishing with just 11 points and going 1-for-2 from deep, and a lot more is expected from the Cavaliers’ best scorer off the bench. In his last 10 games, Hunter has knocked down a pair of triples 8 times, shooting it at an impressive 46% success rate on 2.3 makes per game.

During the regular season, Indiana was a borderline top-10 team in opponent three-point percentage, but over their last 3 games that number is up by almost 2% to 37.4%. After struggling heavily in Game 1 from downtown, I think it’s time for a bounce back from the Cavaliers as a team, hopefully led by a strong Hunter performance off the bench.

Aaron Nesmith over 4.5 rebounds (-136)

Nesmith has made a conscious effort to get rebounds over his past 6 games, averaging 6.7 boards a night this postseason. That’s quite the improvement compared to his regular-season numbers, where he averaged 4 per game, and he is a typical example of a role player stepping up his effort when it matters the most. I’m looking for him to maintain that level of play in Game 2 against a Cavaliers team that allows the 6th-most rebounds to opposing small forwards this season.

It’s quite obvious that rebounds are the Achilles heel of this Cavs team defensively, so look for Nesmith to clear his line on most nights in this series. In the last 8 games against Cleveland, he’s logging 6 rebounds per game and has cleared this line 6 times. In Game 1, the Pacers allowed 13 offensive rebounds by Cleveland, and I’m sure a priority for Game 2 will be to get that number into single digits. Nesmith should play a huge part in that happening for Indiana.

Filip Tomic
Top Trends
Money Line

The Pacers have won 3 straight games against the Cavaliers.

Point Spread

The Cavaliers are 3-7 ATS in their last 10 games as a home favorite.

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