Indiana Pacers vs Denver Nuggets Prediction, Odds and Picks for Today, 11/08/25

The Denver Nuggets will be on the second night of a back-to-back tonight against the Indiana Pacers, but they should be ready for the challenge. The Golden State Warriors did not put up much resistance, as the Nuggets won every quarter on the way to a 25-point blowout. It allowed for all but 2 players for the hosts to play under 30 minutes, which means fatigue might not be a major factor on Saturday. It will help tonight that the visiting Pacers are lacking depth tonight. T.J. McConnell and Tyrese Haliburton are out, Andrew Nembhard is questionable and Bennedict Mathurin missed the last game due to a toe injury. With such a depleted backcourt, it’s no surprise they have just 1 win so far this season.

The Nuggets have been leading the league in offensive rating so far this season. Nikola Jokic has been at the heart of that, averaging 11.6 assists per game. No other player in the NBA is in double-digits in that category. The Pacers will struggle dealing with his size, and that of his backup Jonas Valanciunas. Against such a high-powered offense, the Pacers should have trouble keeping up. The visitors are just 28th in the NBA in 3-point percentage and in the bottom 10 of 3-pointers made. It should give the Nuggets a great chance to cover the spread.

Pacers vs Nuggets prediction: Denver -11.5 (-110) available at time of publishing. Playable at that number.

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