Los Angeles Clippers vs Memphis Grizzlies Prediction, Odds and Picks for Today, 12/05/25

The Los Angeles Clippers have been in the headlines this week after they parted ways with arguably their franchises best player of all time, Chris Paul. As decisive of a decision it was, it did result in a Clippers win on Wednesday against the Atlanta Hawks. The Clippers won 115-92 behind 27 points from James Harden, snapping a 5-game losing streak. Harden and Kawhi Leonard are both set to be in the lineup tonight, looking to make it 2 straight wins. Their opponent tonight will be the Memphis Grizzlies. The Grizzlies are 9-13 this season, with a record at home of 4-6. The Grizzlies have won 3 of their last 4 games, but they did fall short in their last outing against the San Antonio Spurs, 126-119. The Grizzlies led that game with 4 minutes left, but they could not close out a Spurs team that was playing without Victor Wembanyama. 

The most notable injury to report for tonight’s game is the absence of Ja Morant. Morant will continue to miss time with a calf injury. The Grizzlies’ success has actually come with Morant on the sideline. Since his injury, Memphis owns a record of 4-2 without Morant in the lineup. One of the wins the Grizzlies had during that stretch was against the Clippers on November 29, 112-107 on the road despite 39 points from Kawhi Leonard. To avoid 2 straight losses to Memphis, the Clippers will need to slow down center Zach Edey. Edey is enjoying one his best stretches in his young career. Edey is averaging 14.2 points and 11 rebounds per game this season. He recently had a game against the Kings in which he scored 32 points and gathered 17 rebounds. Edey’s play paired with the star capability of Jaren Jackson Jr. has presented a lot of problems for opposing teams. Despite the recent win, the Clippers have been ice cold this season. The Grizzlies are playing much better basketball and will be on their home floor tonight. I like for Memphis to find a way.

Clippers vs Grizzlies prediction: Memphis ML (+105) available at time of publishing. Playable at that number.

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