Los Angeles Lakers

Los Angeles Lakers vs Oklahoma City Thunder Prediction, Odds and Picks for Today, 11/12/25

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7-4-0ATS Record6-5-0
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Oklahoma City Thunder

Lakers vs Thunder Pickswise Expert Predictions

Money Line Pick
LA Lakers Win(+210)

It’s a Wednesday night matinee in Oklahoma City with the LA Lakers coming to town. Luka Doncic and co. have been on fire so far this season, they recovered well from their defeat against Atlanta the other day by beating the lowly Hornets 121-111 on Monday. Things get a lot tougher this evening with the defending champs standing in their way. The last two meetings between the teams were blowout wins, this time around I’m hoping for a slightly more competitive game.

OKC will be playing on a 2nd night of a back-to-back here, which could impact them a little. I say a little because this team has been ruthless in their approach so far, beating teams by an average of 14.4 points per game and winning 11 of 12 games so far. You’ll be hard pressed to find a weakness for this team, even with 5 players on the injury report. SGA is putting together an early case for MVP honors, if the Thunder continue winning at this pace we’ll see a lot of records broken in the coming weeks and months.

The incentive to win will be slightly bigger than normal here, given that this is a nationally televised game after all. The Thunder are a flawless 5-0 at home, but something tells me the Lakers and especially Doncic will be ready here. The man who gifted the Lakers their new superstar just got fired, can you imagine the storylines if the Lakers inflict the defending champs their first home loss of the season just a day after that? It is a risky play, but I’ll take LA to upset here.

Lakers vs Thunder Predictions: Lakers ML is available at +210 odds at time of publishing.

Long-time NBA fan, following the game closely for 21 years now. Joined the Pickswise writing staff for the 2020-21 season and have given out winning picks since. Hopefully we can make some money together! Oh, and I firmly believe Lebron James is not one of the two best basketball players of all time. Yeah, I said it. For Filip Tomic media enquiries, please email contact@pickswise.com.
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Same Game Parlay

Point Spread
LA Lakers +7.5
Game Totals
Under 230.5
Player Threes Made
A. Reaves (LAL) - Over 2.5 threes

LA Lakers +7.5 over OKC Thunder (-110)

Despite LeBron being on the shelf for the time being, Luka Doncic and company have been on fire in the early stages of 2025-26. They took a surprising loss to a depleted Atlanta squad this past weekend, but that was an aberration as opposed to the rule and it was followed by a routine 121-111 dub over Charlotte on Monday. Los Angeles is back on track heading into this huge matchup on Wednesday, and it’s one I actually think the underdogs could even win outright.

There is no denying that the Thunder are the best team in the NBA, but they are playing the second leg of a back-to-back situation after beating the Warriors on Tuesday. Their only loss so far this season? You guessed it – the last time they played a back-to-back (last Wednesday at Portland). While L.A. is without LeBron, keep in mind that OKC is down Jalen Williams, Luguentz Dort and Aaron Wiggins. Give me the Lakers to cover.

Under 230.5 (-110) 

The under correlates nicely with a Lakers cover, because – even with Doncic and Reaves in fine form – I’m not sure they have the firepower to keep up with the Thunder in a shootout. Los Angeles is playing at the sixth-slowest pace in the league (102.5 possessions per game) and over the last 3 contests that number is down to fewer than 100 possessions per contest. With the Thunder playing their second game in as many nights, they may be content to play down to their opponent’s pace. OKC leads the entire NBA in scoring defense by a country mile (108.3 ppg), while L.A. has allowed no more than 116 points in 5 of its last 7 outings. 

Austin Reaves over 2.5 made threes (-144) 

Oklahoma City is the best defensive team in the association, but arguably its one weakness comes at the perimeter. The Thunder are giving up the fourth-most three-pointers per game in the NBA (14.9) on the seventh-highest shooting percentage from downtown (37.3). It’s safe to assume that Raves should be able to capitalize. The Oklahoma product is pouring in 30.1 ppg so far this season while draining 2.9 triples per game. He has attempted a ridiculous 24 threepointers in the last 2 contests alone; in fact, he has not forked up fewer than 8 threes in any of the last 6 games.

Top Trends
Game Totals

The Over is 7-1 in the Lakers' matchups against Western Conference teams this season.

Money Line

The Thunder have won 14 of their last 17 matchups against Western Conference teams.

Point Spread

The Lakers have gone 5-1 on the road against the spread this season.

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