Memphis Grizzlies vs Los Angeles Clippers Prediction, Odds and Picks for Monday, 12/15/25

The Grizzlies come into this matchup emphasizing control and defense, especially with Zach Edey sidelined due to an ankle stress reaction. Before the injury, Edey was averaging 13.6 points, 11.1 rebounds and 1.9 blocks per game — and his absence has forced Memphis to slow the game and lean more heavily on half-court execution. Jaren Jackson Jr. has taken on a larger scoring and rim protection role, while the offense has been more deliberate overall. That approach showed up in their recent 107-98 win over the Clippers, a game in which Memphis dictated tempo, limited transition chances and forced Los Angeles into inefficient possessions.

The Clippers have struggled to find consistency on both ends, sitting near the bottom of the league in defensive efficiency while allowing more than 118 points per game on the season. While they have capable scorers, their offense has been prone to dry spells, often relying on isolated runs rather than sustained scoring. Recent head-to-head results between these teams point toward lower-scoring outcomes, with multiple meetings finishing in the low 200s. Given Memphis’ preference for a slower pace, L.A.’s uneven offensive flow and the defensive nature of their recent matchups, this game profiles more as a grind than a shootout.

Grizzlies vs Clippers prediction: Under 228.5 (-110) available at time of publishing. Playable to 227.

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