Miami Heat vs Chicago Bulls Prediction, Odds and Picks for Friday, 11/21/25

The Chicago Bulls will host the Miami Heat Friday night for an NBA Cup group stage game. The Bulls have a record of 8-6 this season and are currently 1-1 in NBA Cup games. They have been excellent at home, winning five of their six games played in Chicago. The Bulls have won their last two games, with their last win coming against the Portland Trail Blazers 122-121. The close contest concluded with a Nikola Vucevic buzzer-beating three-point shot off an assist from Coby White. The Bulls did lead by 21 points with nine minutes left in this game, so the late three helped Chicago avoid a full late game collapse.

The Heat have an overall record of 9-6 and an NBA Cup record of 1-1. They have struggled on the road this season, losing five of seven games played away from their home court. The Heat have won their last two games, including a 110-96 win over the Golden State Warriors in their last game. Bam Adebayo had 20 points in this game in his return from injury, and the Heat held the Steph Curry-less Warriors to 36% shooting. 

The Bulls have gotten off to a great start to their season, but the cracks in the armor have started to show in the last week. It started with a 150-147 overtime loss against the Utah Jazz. Following the loss, the Bulls let double-digit fourth quarter leads slip away against both Denver and Portland. Chicago won both of those games, but they have shown the signs of being unable to close a ball game out. No lead will be safe tonight against a Miami Heat team that shoots 48% from the field and leads the NBA in pace. Coby White is again listed as questionable for this game after returning from injury. If he can’t go tonight, the Bulls could have a tough time defending the Heats’ backcourt that includes Norman Powell and Davion Mitchell. I like the Heat to outlast the Bulls tonight.

Heat vs Bulls prediction: Miami Heat +2.5 is available at the time of publishing. Playable at that number.

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