Milwaukee Bucks vs Detroit Pistons Prediction, Odds and Picks for Today, 12/06/25

The Detroit Pistons were able to take down the Portland Trail Blazers last night and will now be on a back-to-back set, welcoming the Milwaukee Bucks to Little Caesars Arena. They have had success playing without a nights rest this season, winning 3 of 4 such games. The Pistons have, however, recently lost to the Bucks — but they will be taking on a different version of that team today. Giannis Antetokounmpo is out for the visitors along with AJ Green. The latter has shot over 48 percent from deep this season and scored 19 points when the teams last met. Along with the former MVP, Green will be a big miss.

The Bucks have been on a poor run of form, having lost 8 of their last 10 games. During this stretch they have been in the bottom 10 in both offensive and defensive ratings. It is no surprise that they are coming into this game after a 15-point loss to the Philadelphia 76ers in their last outing. The Pistons have been in the top 10 in offensive rating this season and should prove to be too hard for the Bucks to slow down. Detroit will be helped by the fact that the Bucks are just 23rd in pace this season and also in the bottom 10 in fast-break points per game. It is exactly the type of opponent you would want to play to end a back-to-back. The Pistons should be well positioned to cover.

Bucks vs Pistons prediction: Detroit -12.5 (-110) available at time of publishing. Playable at that number.

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