Oklahoma City Thunder vs San Antonio Spurs Prediction, Odds and Picks for Today, 02/04/26

The Oklahoma City Thunder and San Antonio Spurs will add another chapter to their 2025-26 rivalry when they meet again in San Antonio on Wednesday night. Oklahoma City won the most recent encounter at home on January 13, but the Spurs still lead the head-to-head series this season 3-1 — including a victory in the NBA Cup semifinals. The last time these 2 powerhouses squared off in San Antonio, Victor Wembanyama and company cruised 130-110 on December 23. With home-court advantage against an opponent that has cooled off a bit of late, San Antonio is the way to go in my Thunder vs Spurs pick.

OKC (40-11) is still the best team in the NBA, of course, but it is just 3-4 in its last 7 outings and 5-5 in its last 10. Jalen Williams (16.8 ppg, 5.6 apg, 4.8 rpg) is expected to miss his ninth consecutive contest due to a hamstring injury. As if all of that isn’t enough, the Thunder are playing the second leg of a back-to-back situation (they beat Orlando on Tuesday). The Spurs may not be completely on fire, either, but they are a respectable 6-3 in their last 9 games and have lost at home only once since January 3. San Antonio has great value as a slight underdog, and it should probably even prevail outright on Wednesday night.

Thunder vs Spurs prediction: San Antonio -2.5 (-115) available at time of publishing. Playable to pick ’em.

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