HomeCollege FootballCollege Football PredictionsDuke Blue Devils vs Syracuse Orange Prediction, Odds and Picks

Duke Blue Devils vs Syracuse Orange Prediction, Odds and Picks for Saturday, 09/27/25

Updated: 5:00 AM ET Sep 28, 2025

JMA Wireless DomeACCN

2-2

Duke

12:00 PM ETSat Sep 27

3-1

Syracuse

Joe Williams

Updated: 5:00 AM ET September 28, 2025

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