Boston Red Sox vs Baltimore Orioles Prediction, Odds and Picks for Today, 08/27/25

The Boston Red Sox will look to secure an early series win in their four-game set against the Baltimore Orioles. Through the first two games, Boston has outscored Baltimore 9-3. On the mound today for the Red Sox will be Brayan Bello, entering with a 10-6 record and 3.07 ERA on the season. Bello has been fantastic in his last few starts, going 4-1 with a 2.25 ERA in his last 5 starts. 

For the Orioles, it’s likely they’ll be rolling with their bullpen in this one. The left-hander Dietric Enns is expected to make his third start of the year, entering with a 1-2 record and 4.97 ERA. The Orioles have a 4.69 bullpen ERA this season, which could be a problem for the Orioles in this matchup if they hope to hang around in this one and try to steal a win. The Red Sox are playing much better baseball right now than the Orioles, plus they have the better pitcher on the mound. Look for Bello and the Red Sox to roll, making them my best bet of the day. 

Red Sox vs Orioles prediction: Red Sox ML (-150) available at time of publishing. Playable at that number.

If you’re looking for a new sportsbook, check out Bet365, the world’s #1 sportsbook. They have an amazing sign-up offer where you can INSTANTLY receive $150 in bonus bets from a $5 wager, regardless of whether that bet wins or loses! There’s no catch, it’s really that simple. Join Bet365 right now ⏰ in time to fade or follow our experts’ Red Sox vs Orioles predictions.