Boston Red Sox vs Baltimore Orioles Prediction, Odds and Picks for Today, 08/28/25

I look for the Boston Red Sox to win by multiple runs as they take on the Baltimore Orioles in Thursday’s matchup. Boston is turning to Garret Crochet, who will make his 27th start of the season for the Red Sox in his debut season with the club. Through 166.1 innings of work, the southpaw hurler has posted a 2.38 ERA with 207 strikeouts along the way. He enters this game in good form as well with 14 innings of 2-run ball in his last 2 starts.

Cade Povich is set to start this game for the Orioles. Baltimore’s left-hander has not had as impressive of a season, posting a 5.13 ERA through his first 86 innings of work. This includes 4 earned runs with 2 additional unearned runs surrendered to the Astros in his last outing. Boston is a streaky offensive unit, but they should take advantage of this matchup and provide Crochet with enough run support to win this bet.

Red Sox vs Orioles prediction: Red Sox -1.5 (-105) available at time of publishing. Playable to -110 odds.

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