Chicago Cubs vs Colorado Rockies Prediction, Odds and Picks for Today, 08/29/25

I expect the Chicago Cubs to roll in their matchup with the Colorado Rockies on Friday, August 29. Cade Horton is set to start for the Cubs, marking his 19th appearance of the season for Chicago. Horton enters this matchup in terrific form, having allowed no more than 1 earned run in any of his last 7 appearances. That 7-start stretch has totaled 37 innings with just 2 earned runs allowed total, which is about as dominant of a stretch as you can have. While Horton will make this start in the daunting Coors Field, I still expect him to produce a strong start.

The Rockies will activate German Marquez off the injured list in order for him to make this start on Friday. Marquez has been out since late July, and he has only totaled 98.1 innings of work so far this season. The former ace of this Rockies pitching staff is no longer the arm he once was, and his 1.64 WHIP and 5.67 ERA are highly concerning marks. Facing a tough Cubs lineup is no easy task for any starter in MLB, let alone the first start back from the IL for Marquez.

Cubs vs Rockies prediction: Cubs -1.5 (-150) available at time of publishing. Playable at that price.

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