Chicago Cubs vs Philadelphia Phillies Prediction, Odds and Picks for Today, 04/13/26

Both the Chicago Cubs and the Philadelphia Phillies enter this series with a 7-8 record. Both teams are coming off a series loss, but I find it more likely that the Phillies regain form. Chicago was fortunate to avoid the sweep from Pittsburgh on Sunday, winning dramatically on a walk off after trailing by 5 runs. They did not impress me too much in that series, striking out a ton at the plate while sporting a so-so bullpen. Javier Assad is the scheduled starter for Chicago on Monday as the right-hander looks to make his 2nd start of the year. Assad tossed 5.2 scoreless frames against the Rays in his season debut but is not someone I have been fond of betting on over the years. I don’t love his inability to gain whiffs, especially if dealing with runners in scoring position.

Christopher Sanchez, on the other hand, is someone I love to bet on. The Phillies southpaw starter has taken over the role of the team’s ace this season with Ranger Suarez in Boston and Zack Wheeler still injured. Sanchez posted a 2.50 ERA across 202 innings last season while recording 212 strikeouts. He was dominant with earning ground balls, and his low walk rate helped him remain efficient. Chicago is currently just 16th in wOBA against southpaw pitching while the Phillies are 6th in that category against right-handers. Look for the Phillies to open this series with a multi-run win.

Cubs vs Phillies prediction: Phillies -1.5 (+118) available at time of publishing. Playable to +115 odds.

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