Cleveland Guardians

Cleveland Guardians vs Chicago White Sox Prediction, Odds and Picks for Today, 07/12/25

Rate FieldCHSN
Guardians
44-49
Guardians
Today
White Sox
32-63
White Sox

Vote on who will win!

Chicago White Sox

Guardians vs White Sox Pickswise Expert Predictions

Cleveland Guardians
Money Line Pick
CLE Guardians Win(-150)

Saturday’s matchup between the Cleveland Guardians and Chicago White Sox is not my favorite game on the loaded slate, but I do lean slightly towards a Guardians win in this spot. Tanner Bibee has had somewhat of a rollercoaster season, but he is my preferred starter in this matchup. Sean Burke began the season well for the White Sox, but his last start resulted in 3 home runs and 6 earned runs against the Blue Jays. While he is capable of providing a solid start like he did the outing before against the Dodgers, Burke’s inconsistency makes him hard to back when the White Sox lineup is the one providing run support for him.

Bibee has his own inconsistencies, but I have seen him lead a pitching staff before and I expect his post all-star performance to be much improved from what we’ve seen so far. The White Sox lineup is not one that strikes fear in many opposing starters, and if Bibee can fill the strike zone with pitches early in counts I think he can cruise in this spot.

Cleveland Guardians vs Chicago White Sox prediction: Guardians ML (-150) available at time of publishing. Playable at that price.

Chicago White Sox
Photo of Javan Shouey

Javan Shouey

A lifelong sports fan from Northwestern Pennsylvania. Die-hard supporter of the Steelers, Pirates and Cavaliers. Insane passion for writing about sports and helping others improve. Incredibly thankful for the platform Pickswise is giving me. For Javan Shouey media enquiries, please email contact@pickswise.com.
Read more about Javan Shouey
Pickswise
*
By signing up you agree to our terms and privacy policy