Cleveland Guardians vs Tampa Bay Rays Prediction, Odds and Picks for Today, 09/07/25

I lean towards the under on the posted game total in Sunday’s matchup between the Tampa Bay Rays and Cleveland Guardians. While this game will be played in the hitter-friendly George Steinbrenner Field, I am a fan of the recent form of both starting pitchers in this game. Drew Rasmussen is set to start for Tampa Bay, marking his 28th start of the season. He enters play with 134.2 innings under his belt in 2025 and a 2.74 ERA. It has been another strong season for the right-hander, and I am expecting another effective outing Sunday as he takes on the Guardians. Rasmussen tossed 6 innings of 2-run ball just 10 days ago against this same lineup.

Parker Messick is a 24-year-old southpaw starter set to make his 4th MLB start of his career in this game. His MLB debut resulted in 6.2 innings with just 1 earned run allowed against Arizona. He followed that start up with 7 innings of 1-run ball against the Tampa Bay lineup he will face today. His last outing was his worst so far, lasting just 3.2 innings while surrendering 3 earned runs along the way. Overall, though, I have been impressed by his early returns, and I expect him to pitch well again in this outing.

Tampa Bay Rays vs Cleveland Guardians prediction: Under 8 (+100) available at time of publishing. Playable at that price.