Detroit Tigers

Detroit Tigers vs Boston Red Sox Prediction, Odds and Picks for Today, 09/28/25

Fenway ParkNESN
Tigers
87-74
Tigers
Today
Red Sox
88-73
Red Sox

Vote on who will win!

Boston Red Sox
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Tigers vs Red Sox Pickswise Expert Predictions

Detroit Tigers
Game Totals Pick
Over 9.0(-110)

The Boston Red Sox and Detroit Tigers are both headed to the postseason as wild card teams for the American League in 2025. Detroit held onto a playoff spot at the very end despite blowing a large divisional lead to the Guardians. Boston battled all season long in the tough AL East that will send 3 teams to the playoffs this year. Both teams are prepped for long runs if they can find their form, as both teams possess true aces with quality depth behind them from a pitching perspective. Despite this I lean towards the over on the posted game total for this game.

Chris Paddack is set to start for Detroit, marking his 33rd appearance and 12th with the Tigers after starting with Minnesota. In 153.2 total innings the veteran right-hander has posted a 5.27 ERA. In 42.2 innings with Detroit that mark jumps to 6.12. Expect runs for Boston in this spot. The Red Sox have yet to announce a starter for this game but don’t figure to use their main arms if possible, given upcoming Wild Card game.

Detroit Tigers vs Boston Red Sox prediction: Over 9 (-110) available at time of publishing. Playable at that price.

Boston Red Sox
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Javan Shouey

A lifelong sports fan from Northwestern Pennsylvania. Die-hard supporter of the Steelers, Pirates and Cavaliers. Insane passion for writing about sports and helping others improve. Incredibly thankful for the platform Pickswise is giving me. For Javan Shouey media enquiries, please email contact@pickswise.com.
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