Philadelphia Phillies vs Miami Marlins Prediction, Odds and Picks for Today, 09/05/25

I expect the Philadelphia Phillies to win by multiple runs Friday as they take on the Miami Marlins. Cristopher Sanchez is set to start for the Phillies in this game, and he is the main reason for my confidence in his team. With Zack Wheeler out for the season in Philadelphia, Sanchez is now the clear ace of this staff for the remainder of the season. The southpaw hurler has been outstanding in 2025, posting a 2.66 ERA with 181 strikeouts across his first 169.1 innings of work. He is able to succeed by finding that 3rd strike or by way of his ground balls that he induces at an above-average rate.

Valente Bellozo is scheduled to open this game for the Marlins as the right-hander makes his 28th appearance and 6th start of the season. Bellozo faced 19 batters in his last outing, tossing 65 pitches and recording 13 outs to his name. This is about as deep into the game as we should expect him to go, as he has been primarily used as a multi-inning reliever with the Marlins. Regardless, Philadelphia holds the offensive firepower to provide run support for Sanchez and win by multiple runs.

Phillies vs Marlins prediction: Philadelphia -1.5 (-165) available at time of publishing. Playable at that price.

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