San Diego Padres vs Los Angeles Dodgers Prediction, Odds and Picks for Monday, 06/16/25

The San Diego Padres roll into Los Angeles to battle at Dodger Stadium for the first of 4 games on Monday night. If you were worried about the protests and demonstrations, and the subsequent curfew in L.A., relax. The games have gone off as scheduled, as the stadium lies outside of the downtown curfew area. RHP Dylan Cease is on the bump for the visitors, as he looks to lock up the bats of the Dodgers for a second straight time. He spun seven scoreless innings in an 11-1 laugher against the Dodgers last Tuesday at Petco Park, and he has a career 1.95 ERA against L.A. There is something about the Dodgers that gets Cease fired up.

For the Dodgers, they will welcome RHP Shohei Ohtani back to the mound. It’s actually going to be his pitching debut in Dodger Blue, as he hasn’t appeared on the mound in an MLB game since Aug. 2023 when he was with the Los Angeles Angels. Following a bevy of injuries, he will get back on the hill — but there will be obvious concerns about pitch count, rust, etc. With the way Cease commanded his pitches against the Dodgers last week, and the question marks surrounding Ohtani as a pitcher, the value is on the visitors.

Padres vs Dodgers: San Diego ML (+130) available at time of publishing. Playable to +115.

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