San Diego Padres vs Milwaukee Brewers Prediction, Odds and Picks for Saturday, 06/07/25

On May 23 and 24 the Brewers lost back-to-back games against the Pittsburgh Pirates to fall to 25-28 on the season. They have since won 9 of their last 11 games including sweeps of the Red Sox and Phillies to reach 34-30 as they enter today’s game. San Diego won Game 1 of this series to jump to 36-26, but they have been just sort of coasting since their 14-3 start. These teams will each start a left-hander today with Stephen Kolek for the Padres and Jose Quintana for the Brew Crew. Kolek has made 6 starts so far, allowing 0 earned runs in 20 combined innings against the Giants, Rockies, and Pirates including a complete game shutout vs the Rockies. His other 3 outings combined for 16.1 innings with 14 earned runs allowed against the Mariners, Blue Jays, and Marlins. Kolek faces a Brewers lineup today that ranks 9th in wOBA with a 99 wRC+ across 359 PA since May 1.

Quintana had a poor start against the Cubs with 6 earned runs and 3 home runs allowed, but his other 6 starts have combined for just 6 earned runs and 2 home runs. His underlying metrics suggest eventual regression, but today he will face a San Diego lineup that ranks just 22nd in wOBA with a wRC+ of 82 against southpaw pitching since May 1. The veteran hurler should be able to find some success in this spot, and I like the Brewers to win this game.

San Diego vs Milwaukee Brewers predictions: Brewers ML (-115) available at time of publishing. Playable to -120 odds.

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