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HomeMLBMLB PredictionsSt. Louis Cardinals vs Cleveland Guardians Prediction, Odds and Picks

St. Louis Cardinals

St. Louis Cardinals vs Cleveland Guardians Prediction, Odds and Picks for Saturday, 06/28/25

Updated: 6:00 AM ET Jun 29, 2025

Progressive FieldFanDuel SN

45-38

Cardinals

4:10 PM ETSat Jun 28

40-40

Guardians

Cleveland Guardians

Javan Shouey

Updated: 6:00 AM ET June 29, 2025

Show Bio

A lifelong sports fan from Northwestern Pennsylvania. Die-hard supporter of the Steelers, Pirates and Cavaliers. Insane passion for writing about sports and helping others improve. Incredibly thankful for the platform Pickswise is giving me. For Javan Shouey media enquiries, please email contact@pickswise.com.

Read more about Javan Shouey

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May 20, 2022; Cleveland, Ohio, USA; Detroit Tigers starting pitcher Tarik Skubal (29) delivers a pitch in the third inning against the Cleveland Guardians at Progressive Field.

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