St. Louis Cardinals vs San Diego Padres Prediction, Odds and Picks for Today, 08/03/25

Dylan Cease had numerous trade rumors pop up with his name in them during the trade deadline cycle, but he remains with the San Diego Padres after all as they make a push towards the post season. Cease has not had the season he hoped for, and that may have contributed to his decreased trade value from San Diego’s perspective, but he remains a talented piece of this Padres team, and he is my preferred starter in this matchup. Home runs and walks have been his concern, but he has the strikeout upside to get out of jams and if he can avoid the long ball in this spot the Padres should roll.

Andre Pallante twirled 7 scoreless frames in his last start against the Marlins, doing so in only 81 pitches thrown with 1 hit and 1 walk allowed. It was a dominant outing, but the rest of his season has been far from dominant, posting a 4.91 ERA prior to that start. Pallante is a pitch-to-contact starter who fails to generate many whiffs, and this Padres lineup has recently added several depth pieces to bolster their lineup and bench unit. I lean towards a multi-run win for San Diego today.

San Diego Padres vs St. Louis Cardinals prediction: Padres -1.5 (+120) available at time of publishing. Playable at that price.