Tampa Bay Rays vs Chicago Cubs Prediction, Odds and Picks for Today, 09/14/25

I favor the Chicago Cubs over the Tampa Bay Rays as the teams face off Sunday afternoon. Shota Imanaga is scheduled as the Cubs starting pitcher which is usually a good sign for Chicago bettors. Imanaga has delivered with extreme consistency for Chicago of late, supplying their rotation with a quality start in each of his last 7 trips to the mound. While the Cubs have only won 5 of those 7 starts, Imanaga can only control his side of things, and I expect the Cubs to find some more offensive success in today’s spot against the Rays of Tampa Bay.

Adrian Houser has had a good season in 2025, especially for his expectations. The right-handed veteran posted a 2.10 ERA in 11 starts with the White Sox which caught the eye of trade suitors at the deadline. Tampa Bay pounced and acquired him, but he has not performed as well in his new uniform. In 38.1 innings across 7 starts Houser has posted a 4.93 ERA including 4 or more earned runs in 4 of those outings.

Chicago Cubs vs Tampa Bay Rays prediction: Cubs ML (-165) available at time of publishing. Playable to -170 odds.