Tampa Bay Rays vs Minnesota Twins Prediction, Odds and Picks for Today, 04/03/26

Both the Tampa Bay Rays and Minnesota Twins enter with records of 2-4 on the young season when they meet on Friday night at Target Field. The Rays have a tough draw playing their first 3 series of the new campaign on the road, and this will be their 7th consecutive road game to start the season. The Tampa Bay bats started off hot, scoring 23 runs in 3 games against St. Louis. However, they have cooled off significantly since then, scoring just 7 total runs in their 3-game series against Milwaukee earlier this week. Minensota starting pitcher Bailey Ober had a rough first outing, but he seems to be in a decent position to bounce back in this one.

This game serves as the home opener for the Twins. Minnesota has scored 14 runs over its last 2 games, so the offense enters this matchup in more of a groove than Tampa Bay’s. Furthermore, the Twins could have an advantage at the plate when going up against the Tampa Bay bullpen. The Rays’ bullpen ERA of 9.15 is the highest in the MLB through the first week of the season. In addition, opposing hitters own a strong .349 average against Tampa Bay relievers. That should give the Twins the edge in this one. Playing their first home game of the season, back the Twins on the moneyline.

Rays vs Twins prediction: Minnesota Twins ML (-110) available at time of publishing. Playable at that number.