Texas Rangers vs Cleveland Guardians Prediction, Odds and Picks for Today, 09/26/25

Pricing for the side and total of Friday’s matchup between the Texas Rangers and Cleveland Guardians seems about right to me, as the total of 8 is juiced towards the under with the Guardians favored at -160. Cleveland is tied with Detroit at 86-73 with 3 games remaining for each team. The Guardians hold the tiebreaker, which is crucial for their chances, and a win today would go a long way in locking up the division title. Slade Cecconi is the slated starter for Cleveland Friday evening, as the right-hander is set to make his 23rd start of the season. Cecconi has had a solid season in his first year with the Guardians, tossing 128 innings with a 4.15 ERA. Those are both career-best marks, and his recent performances have been the most encouraging. His last 3 outings have combined for 20.2 innings with just 2 combined earned runs allowed.

Jack Leiter is set to start this game for the Rangers, marking his 29th start of the season. In his 2nd season with the Rangers, Leiter has tossed 144.2 innings while maintaining a 3.92 ERA and registering nearly a strikeout per inning. The 25-year-old has shown promising flashes at times for his squad, and figures to play a large role in their plans for 2026. Leiter has allowed 7 earned runs in his last 2 starts, but prior to that had allowed 3 or fewer earned runs in 14 straight outings.

Rangers vs Guardians prediction: Under 8 (-125) available at time of publishing. Playable at that price.

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