Cleveland Cavaliers vs Portland Trail Blazers Prediction, Odds and Picks for Today, 02/01/26

The Cleveland Cavaliers kicked off a 5-game road trip in Phoenix with a 126-113 loss as -2 favorites in Phoenix on Friday. While that was a bummer, they’re still 4-1 SU across the past five games, including a 129-99 annihilation of the visiting Los Angeles Lakers on Wednesday. The Cavs are also 3-1 against the spread in the past 4 games while going 4-1 ATS in the past five outings on the road. The Cavs won 122-111 in Portland last season, cashing as a 6.5-point favorite. In fact, Cleveland is 4-0 SU/ATS in the past 4 visits to PDX since January of 2022.

For the Trail Blazers, they’re coming off an 0-3 SU/1-2 ATS road trip through the Eastern Conference, wrapping up the trip Friday with a 127-97 beatdown from the New York Knicks. The Blazers have lost four in a row, and they’re 1-3 ATS in that span. The bad news for the Blazers is that leading scorer Deni Avdija remains questionable due to a strained lower back. With Avdija laid up, this team has looked much different, and certainly not for the better. If he plays, the Cavs are still worth a look, but if he is ruled out, go a little more aggressively on Cleveland.

Cavaliers vs Trail Blazers prediction: Cleveland -2.5 (-110) available at time of publishing. Playable to -3.5.

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