Detroit Pistons vs Milwaukee Bucks Prediction, Odds and Picks for Today, 11/22/25

What a difference a year can make. Last year the Pistons won their 13th game of the season on December 30th, this season it took them 40 days less to achieve that feat. The turnaround is truly remarkable, I would imagine not a lot of people had Detroit leading the East after 15 games played, with a 3 game advantage over the Cavaliers. Saturday will see the Pistons take on a wounded Bucks team, with a chance to reverse a trend that’s been going on for the past 3 seasons. Detroit has lost 13 games in a row to Milwaukee dating back to the 2021-22 season, the way things are going right now this is an ideal opportunity to end that streak.

No Giannis for Milwaukee means trouble. The team automatically goes from being the number 1 offense in the NBA all the way to the bottom. Even though they scored 114 on the Sixers in their last game and took Philly to overtime, facing a quality team like the Pistons I feel like the weaknesses of the Bucks will be exposed here. Only the OKC Thunder have a better defensive rating this season than the Pistons do. Ball movement is something the Bucks will struggle with here, Detroit allows the least assists per game this season. They also face the 2nd most turnovers, things just aren’t looking bright for the Bucks at the moment.

Milwaukee is 1-6 ATS in 7 games, they’ve won just once in 5 overall as well. Against East teams they’ve covered the spread only twice in 7 games, they’ll face stiff competition in their next 4 games and if things don’t improve rapidly we could be looking at a 8-12 record before Giannis returns. Pistons have won 11 in a row, they’ve covered 9 times during this stretch. Go with the road squad here.

Pistons vs Bucks Predictions: Pistons -8.5 is available at time of publishing. Playable at that number.