Indiana Pacers vs Chicago Bulls Prediction, Odds and Picks for Today, 12/05/25

There seems to be no end in sight for the issues the Indiana Pacers are suffering from this season. For the 2nd consecutive game they allowed 135 points and lost, this time around to the Denver Nuggets. Containing Jamal Murray looked like a mission impossible on Wednesday, more issues could be ahead on Friday against a Bulls team that’s loaded at the guard positions. Indiana did win the first meeting 103-101, but now the game is being played in the Windy City which is a problem considering the Pacers are 0-13 SU in 13 road games.

Chicago hasn’t had much luck over their last 5 games, but they’ll try to end that losing streak tonight at the United Center where they’re 6-3 SU on the season and have won 13 of 18 games. I feel like it’s only a matter of time until the Bulls turn things around, there’s too much talent on this roster for that not to happen. This team plays the 2nd fastest pace in the league and that’s something the Pacers won’t be too comfortable with given their injury situation.

At 6-3 ATS the Bulls have been relatively reliable in home games. I know it’s not ideal backing a team that’s on a 5-game losing streak, but the Pacers have been pretty bad this season and this is an ideal chance for Chicago to bounce back at home. I’ll take the Bulls.

Indiana Pacers vs Chicago Bulls Predictions: Bulls -5 is available at time of publishing. Playable at that number.