Indiana Pacers vs Los Angeles Lakers Prediction, Odds and Picks for Today, 03/06/26

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The losing streak of the Indiana Pacers has reached 7 games in a row, with their last 4 defeats coming by double-digits. Ivica Zubac returned to LA in street clothes as his new team faced his old team in the Clippers. Indy was routed by 23 points on Wednesday despite getting 29 points from Pascal Siakam. Things could get a lot more difficult on Friday if Siakam isn’t able to play, as he is officially listed as day-to-day with a wrist issue. This is nothing new for the Pacers, who are already missing a bunch of key players, including Nembhard and Nesmith. They’ve not had the best of times versus the Lakers either, winning just once in 6 meetings. At Crypto.com Arena, they’re just 2-9 ATS in 11 visits.

Meanwhile, the Lakers lost a tough one in Denver last night, falling to the Nuggets 120-113 as +5.5 underdogs. Luka Doncic had 27 points, 11 rebounds and 7 assists, while LeBron James surpassed Kareem Abdul-Jabbar for most field goals made all-time in the NBA, but none of that was enough to slow down Nikola Jokic who just destroyed the Lakers down low. Deandre Ayton left the game after just 5 mins with a knee injury, and he is likely to sit this one out against Indiana. This could force the Lakers to play small and in theory a lot faster than what we’re accustomed to seeing from them. I actually like the sound of that plan, that’s where the talent of Luka Doncic excels the most.

In 10 games played with no rest this season the Lakers are 5-5 SU, but they did win their last 3 of 4 such games by 24, 17 and 25 points vs Sacramento, Toronto and Atlanta. Indiana’s Net Rating reads -15.3 during this 7-game losing streak, only two other teams in the NBA are worse than them in this stretch. I’ll back the Lakers even though they’re playing on a 2nd night of a back-to-back.

Pacers vs Lakers prediction: Lakers -10.5 (-105) available at time of publishing. Playable at that number.

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