Indiana Pacers vs New York Knicks Prediction, Odds and Picks for Today, 03/17/26

It feels like a lifetime ago since the Indiana Pacers defeated the New York Knicks in 6 games in the Eastern Conference Finals. Fast forward to present day and the Pacers have a league-worst 15-53 record and have lost 13 straight games. These 2 teams will have their final opportunity tonight to renew this rivalry, which has stayed competitive throughout the season despite the Pacers’ struggles. The Knicks lead the season series 2-1, but both wins were only by single-digits. The last time these teams played in New York was on February 10, when the Pacers took home the win 137-134 in overtime. They just faced each other 4 days ago in Indiana, where they Knicks won 101-92 and each team shot below 42% from the field. The Pacers’ roster is filled with players listed as questionable for this game, including Andrew Nembhard, TJ McConnell and Obi Toppin — so it is difficult to get an early read on who will suit up for Indiana.

All of these injuries should lead me to the Knicks to cover — but based on their recent game against Golden State, I have my doubts. The Knicks were in a similar scenario where the Warriors were missing their top 4 players to injury, but they still allowed Golden State to jump out to a 20-point advantage in the second quarter. Instead, I think the over is the best play for this game. I believe this number is a little bit lower due to these 2 teams’ low-scoring game last Friday. With the Pacers rated as the 25th-worst team according to defensive rating, I do not foresee another poor shooting night from the Knicks — especially not on their home floor. The Pacers are also in the top 10 in the NBA in pace. If the Knicks once again follow suit and this game turns into a track meet like it did the last time these teams met in New York, we could see this game go well above the total.

Pacers vs Knicks prediction: Over 223.5 (-110) available at time of publishing. Playable at that number.