Arizona Cardinals odds, season predictions and best NFL futures bets 2023  

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Ricky Dimon


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Since graduating from Davidson (The College That Stephen Curry Built), I have been writing about sports -- just about any and all you can think of! -- and coaching tennis in Atlanta, GA. Beyond the four major sports, I am an avid tennis fan and cover the ATP Tour on a daily basis. If I'm not busy writing, you can generally find me on a tennis court or traveling the world wherever a sporting event takes me. For Ricky Dimon media enquiries, please email
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The Arizona Cardinals started the 2021 season with a 10-2 record. Since then they have gone 5-18. You can’t make this stuff up, folks. Few franchises in NFL history have fallen farther and faster than Arizona, which is projected to be even worse in 2023 than it was in 2022. Former #1 overall pick Kyler Murray suffered a torn ACL in December of last year and had surgery to repair it in January. It’s hard to see Murray being ready for the start of the regular season and who knows if the Cardinals will still be in mathematical playoff contention by the time he is ready to return? 

Will Arizona be the worst team in the league this season, or will it be able to win more than a few games? Let’s take a look at the odds and best bets to be made on the Arizona Cardinals in 2023. 

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Arizona Cardinals breakdown 

2022 record: 4-13 

2022 ATS record: 8-9 

2022 O/U record: 9-8 

Key players in: Kyzir White (LB), Hjalte Froholdt (C), Zach Pascal (WR) 

Key players out: DeAndre Hopkins (WR), Zach Allen (DE), Byron Murphy (CB), Chosen Anderson (WR) 

2023 NFL Draft class: Paris Johnson Jr. (OT), B.J. Ojulari (LB), Garrett Williams (CB), Michael Wilson (WR), Jon Gaines II (G), Clayton Tune (QB), Owen Pappoe (LB), Kei’Trel Clark (CB), Dante Stills (DT)

Head over to the Pickswise NFL futures guide for odds and predictions on various betting markets 

Arizona Cardinals 2023 NFL season odds

Odds provided by DraftKings Sportsbook 

Arizona Cardinals Super Bowl odds

The Cardinals are +20000 to win Super Bowl LVIII. That puts them tied for last with the Texans. 

Arizona Cardinals NFC Championship odds

Arizona is +10000 to win the NFC, good for dead last by a country mile (the Rams and Buccaneers are +4500). 

Arizona Cardinals NFC West odds

At +2500, the Cardinals are the longshot in the NFC West. They trail the 49ers (-160), Seahawks (+195) and Rams (+1000).

Arizona Cardinals win total odds 

The Cardinals’ win quota is 4.5 games, with the under priced as a -120 favorite and the over coming in with +100 odds. Exact records of 3-14, 4-13 and 5-12 are all +450. 

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Arizona Cardinals 2023 schedule

Week 1: at Washington Commanders

Week 2: vs New York Giants

Week 3: vs Dallas Cowboys

Week 4: at San Francisco 49ers

Week 5: vs Cincinnati Bengals

Week 6: at Los Angeles Rams

Week 7: at Seattle Seahawks

Week 8: vs Baltimore Ravens

Week 9: at Cleveland Browns 

Week 10: vs Atlanta Falcons 

Week 11: at Houston Texans 

Week 12: vs Los Angeles Rams 

Week 13: at Pittsburgh Steelers 

Week 14: BYE

Week 15: vs San Francisco 49ers 

Week 16: at Chicago Bears

Week 17: at Philadelphia Eagles 

Week 18: vs Seattle Seahawks 

We’ll have NFL picks for EVERY matchup of the 2023 season 

Arizona Cardinals 2022 season recap

After compiling a 7-0 record on the way to 10-2 in 2021, the Cardinals never contended in 2022. Not once did they get above .500 and the last time they found themselves at .500 was Week 4. Head coach Kliff Kingsbury’s crew was still somewhat respectable at 4-6 through 10 weeks, but it promptly lost its final 7 games. Although a few contests were competitive, during that closing stretch the Cardinals lost to the 49ers twice by a combined score of 76-23. QB Kyler Murray got hurt during a Week 14 Monday Night Football loss to New England, after which Colt McCoy, Trace McSorley and David Blough split time under center. Results the rest of the way were predictably disastrous, as Arizona finished 4-13 for the third-worst record in football. 

Read our NFC Championship predictions and best bets

Arizona Cardinals 2023 NFL season predictions

As the odds indicate, Arizona is expected to be the worst team in the entire NFL. The Cardinals were already bad last year and now Murray is temporarily gone while WR DeAndre Hopkins is permanently gone. Is there any reason for optimism in 2023, or is it all bad?

Here are a couple of my predictions for the Arizona Cardinals this season. 

Best bet: Arizona Cardinals under 4.5 wins (-120)

This franchise clearly isn’t in win-now mode. Heck, that might have been the case even if Murray had not got hurt. Complete rebuilding mode was confirmed when Arizona traded away the #3 overall pick in the NFL Draft to stockpile future selections. The Cardinals got worse in free agency and drafted projects as opposed to immediate impact players. Looking at the schedule, they may be able to beat the Rams and Seahawks at home,  but otherwise their home lineup is difficult and I can’t see them winning more than 2 games on the road. As low as the number is, I still think the under is the way to play it. 

Arizona Cardinals season record predictions

I would probably avoid the exact wins market with this team given the uncertainty surrounding Murray, but +450 odds on 4-13 arguably represents the best value. The Cardinals should be able to win a couple of games in an NFC West that is unspectacular outside of the 49ers, and they can piece together a couple of other victories along the way. But even if Murray returns and is close to his former self, this team is likely to be bad. 

Find out which players we are targeting for our NFL MVP best bets 

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Pickswise is the home of free expert NFL Picks and NFL Odds. Be sure to check out all of our season previews and NFL Futures Bets leading up to the 2022 NFL season.

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