NFL Preseason Week 3 Sunday best bets: 49ers want it more

San Francisco 49ers quarterback Trey Lance (5) scrambles in the pocket before throwing a pass in the second half against the Los Angeles Chargers at SoFi Stadium
Photo of Andrew Ortenberg

Andrew Ortenberg

NFL· 2 weeks ago

Show Bio

I'm an editor here at Pickswise who was raised in a household full of sports fanatics. Since I unfortunately never had LeBron James' jumping ability I wasn't able to make it to the NBA, and chose writing about sports as the next best thing. An avid sports bettor myself, I'm excited to get to write about the industry as it gets set to take off across the country. Buckle up.

The NFL preseason is officially winding down. The first two weeks have been a ton of fun and the third and final week will wrap up with our last batch of 5 games on Sunday. Here at Pickswise we will be bringing you great NFL content all season, with free picks on sides and totals, parlays, mega parlays, etc.

It’s also not too late to wager on our NFL futures, either, which you can find in our NFL news tab. But right now we’re talking preseason, and specifically these Sunday games. Let’s break down my best bets, with a little note on their parlay odds if you want to pool them together.

San Francisco 49ers -3.5

New England Patriots -3.5

Preseason parlay odds: +264

Let’s break down each play.

San Francisco 49ers -3.5 (-110) over Las Vegas Raiders

It’s clear which team wants to win this one more. Jon Gruden isn’t being as aggressive in this preseason as he has been in the past, and Raiders QB Derek Carr isn’t going to play. On the flip side, it looks like both Jimmy Garoppolo and Trey Lance will see time under center for the 49ers. Kyle Shanahan wants Lance to get as comfortable as possible before he begins his rookie season, so I think we’ll see a lot of him — and Shanahan should put him in good positions.

Last week the Raiders managed to beat the Rams by only 1 point. Sean McVay sits practically his entire roster for preseason games, and barely even fields a team, so Las Vegas’ squeaker of a win certainly wasn’t inspiring. Nathan Peterman should once again get the bulk of the work at quarterback for the Raiders, and he just threw a couple of interceptions to deep Rams reserves.

Be sure to check out our full game preview for Las Vegas Raiders vs San Francisco 49ers

New England Patriots -3.5 (-110) over New York Giants

The Patriots are a preseason force to be reckoned with. They have been downright dominant through their first 2 games, most recently bludgeoning the Eagles 35-0. New England held Philly scoreless, and then the Eagles proceeded to score 31 in their next game, so I’d say they played pretty good defense. The Giants have scored only 20 points through their first two games, both losses, so it’s not like we’ll need an amazing effort from the Pats to cash this anyway.

Like the 49ers, the Patriots also have a first-round rookie quarterback in Mac Jones whom they want to get a lot of work this weekend. After Daniel Jones (who might struggle in his own right), the Giants have only Mike Glennon and undrafted rookie Brian Lewerke at quarterback.

Be sure to check out our full game preview for New England Patriots vs New York Giants

Pickswise is the home of free NFL Predictions  and NFL Odds. Check out the latest NFL Prop Bets and NFL Parlays as well as expert NFL Underdog Picks and NFL Computer Picks.

Virginia Bonuses

See All
DraftKings

$200

Bet $1 On Any NFL Football Game & Get $200 In Free Bets Instantly!

Register for a new DraftKings Sportsbook account

Bet $1 on any Pro Football game

Instantly get $200 in free bets

BetMGM

$200

Bet $10, Get $200 If Your Team Scores A Touchdown!

Register for a new BetMGM account & deposit $20+

Bet $10 on your team to win Money Line

Win $200 in free bets if your team scores a touchdown

21+. Terms & conditions apply.

FanDuel Sportsbook

$150

Bet $5, Win $150 if the Chiefs or Ravens win!

Make a new account with FanDuel Sportsbook

Bet $5 on either the Chiefs or Ravens to win their Week 2 matchup

If your team wins, you win $150 cash!

New players only. Max bet $5. Must be 21+ to play. Full terms available at FanDuel Sportsbook.

PointsBet

$200

Bet $20, Get $200 If Your Team Scores A Touchdown!

Register for a new PointsBet account & deposit $20+

Bet $20 on your team to win Money Line (NFL or NCAAF)

Win $200 in free bets if your team scores a touchdown

Caesars Sportsbook

$5,000

Get a $5,000 Risk Free Bet + a free NFL Jersey!

Register for a new Caesars Sportsbook account & make a deposit

Place your first bet up to $5,000 risk-free!

Get refunded up if you lose up to $5,000 + a free NFL Jersey

21+. Terms & conditions apply.

BetRivers

$250

Get a $250 Deposit Bonus!

Sign up for a new BetRivers account using promo code PICKSWISE

Make a deposit & get it doubled up to $250 total

To get a $100 bonus, deposit $100

Must be 21+. Play in IA Only. Gambling Problem? Call 1-800-BETS OFF

BetMGM

$1,000

Get a $1,000 Risk Free Bet!

Register for a new BetMGM & deposit

Place your first bet up to $1,000 risk-free!

Get refunded up if you lose up to $1,000

21+. Terms & conditions apply.

FanDuel Sportsbook

$1,000

Get a $1,000 Risk Free Bet!

Register for a new FanDuel Sportsbook account & deposit

Place your first bet up to $1,000 risk-free!

Get refunded up if you lose up to $1,000

21+. Terms & conditions apply.

DraftKings

$1,000

Get a $1,000 Deposit Bonus!

Register for a new DraftKings Sportsbook account & deposit

DraftKings will match 20% of your deposit up to $1,000 total

To get a $100 bonus, deposit $500

21+. Terms & conditions apply.

Monkey Knife Fight

$100

Claim 100% Instant Deposit Match up to $100!

Register for a Monkey Knife Fight account & deposit using promo code PICKSWISE100

Monkey Knife Fight will match your first deposit up to $100

Deposit $100 and you'll get $100 bonus + a free $5 game

18+. Terms and conditions apply. You must live in one of the states where real money DFS is legal.

TVG

$300

Get a $300 Risk-Free Bet with TVG Racebook!

Register for a new TVG account and make a deposit

Place your first single horse win-type bet up to $300

If your horse doesn't win you'll get a refund up to $300

21+. T&C's apply. Please gamble responsibly.

BetAmerica Racing

$200

$200 Sign Up Bonus!

Fast, reliable and fast payouts - you'll have your money in 72 hours, if not sooner!

Proud history of providing safe, secure, and fun betting to American patrons

BetAmerica is owned by the iconic Churchill Downs Incorporated, home of 150 years of wagering history and the world-famous Kentucky Derby

Players who sign up using ‘BET200’ code will get a $200 sign up bonus. Offer valid for 7 days after registering on BetAmerica Racing product only. 21+. T&C's apply. Please gamble responsibly.

TwinSpires

$200

Get a $200 Sign Up Bonus with TwinSpires Racebook!

Register for a new Twinspires account using offer code BET200

Make a deposit and start wagering on horse racing

Earn $100 in bonus cash for every $400 wagered!

21+. T&C's apply. Please gamble responsibly.