TNF NFL Betting Guide: Packers vs Lion picks, expert predictions, odds & best bets

UpdatedSep 15, 2026

Reading time2 min

We’ve got perhaps the biggest Thursday Night Football matchup of the season kicking off NFL Week 14 as the Green Bay Packers take on the Detroit Lions in a crunch game in the NFC North. The Lions pulled off their first Thanksgiving victory last week against the Bears to move to 11-1 but Jared Goff and company certainly made it harder for themselves than it needed to be. As for Green Bay, they comfortably beat the Dolphins on the same day and will be confident they can make a statement at Ford Field after Jordan Love tore it up there last season.

Packers vs Lions gets underway at 8:15 pm ET live on Amazon Prime Video, and here at Pickswise, we have everything you need to bet better on this great Thursday Night Football game, including NFL picks on the side and total, expert NFL player prop bets from our props betting experts including Prop Holliday and JutPicks, as well as a Packers vs Lions Same Game Parlay after we hit FOUR SGPs last week! Let’s get into our TNF picks and Packers vs Lions predictions.

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NFL TNF picks & Packers vs Lions predictions

Green Bay Packers vs Detroit Lions predictions — our expert is on a 16-6 run!

Packers vs Lions best player prop bets

Packers vs Lions player prop picks — find out Prop Holliday’s best bet for tonight, featuring Sam LaPorta
Packers vs Lions touchdown scorer best bets — we’re up +12.9 units on our TD scorer picks over the past 2 weeks!

Green Bay Packers vs Detroit Lions Same Game Parlay

Packers vs Lions Same Game Parlay — we hit FOUR NFL SGPs last week at +617, +612, +649 and +675 odds! Find out our red-hot expert’s picks for TNF

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