Wise n' Shine: MLB picks and predictions for Tuesday, September 27

Good morning, Pickswise Nation. Following last night’s Monday Night Football game, we’re without football for the next few days. But don’t worry! There’s plenty of MLB action on the board today. It’s another big day in the world of sports, so let’s not waste any time and get right to making your next bet better with Wise n’ Shine!

About Last Night

Cowboys top Giants in NFC East battle
No Dak, no problem. The Cowboys defeated the Giants 23-16 on Monday night to complete Week 3 of the NFL season. We hit our best bet of Saquon Barkley to find the end zone at +105, so it rounded out an excellent week of NFL football for the Pickswise handicapping team. So after 3 weeks, the only undefeated teams left are the Miami Dolphins and the Philadelphia Eagles (just as everyone predicted).

Today’s Slate

Back to a 15-game MLB slate
It was a small slate of 4 games on Monday night, but the MLB is back in action today with a full 15-game slate. The Rays-Guardians start the day off at 6:10 pm ET, and the Rockies-Giants will conclude the day at 9:45 pm ET. Be sure to read all of our MLB picks.

Best Bet of the Day

MLB: Baltimore Orioles vs Boston Red Sox under 9 runs
7:10 pm ET, NESN

Michael Wacha has been excellent against the Orioles this season with a 2.31 ERA. Combine that with him starting at home, where he has been excellent all season long, and you have a low-scoring game. In his 9 starts at Fenway, the average score of the games is just 7.55 runs which is nearly a run and a half below the total for Tuesday’s game. As for Kyle Bradish, he has had a successful season after the all-star break. In those 11 starts, opponents are hitting just .210 off him, and he has a 2.67 ERA. In his most recent start, which was against the Astros, he tossed 8.2 innings without allowing a run, only allowing 2 hits, and recording 10 strikeouts. In his most recent start against the Red Sox, he surrendered just 1 run throughout 7 innings while also allowing just 2 hits. In what should be a better pitching showdown than the oddsmakers predict, take the under with confidence. Check out our Orioles vs Red Sox predictions.


We’ve got plenty of MLB action today and we couldn’t miss the opportunity for a +845 MLB mega parlay, especially after we hit Sunday’s mega parlay! And of course, our YRFI/NRFI bets have been hot all season long and our expert has his 2 favorite YRFI/NRFI picks for today picked out.

On the college gridiron, we are already looking ahead to the upcoming week by breaking down the NCAAF opening lines.

Check out more great content as it arrives throughout the day on the Analysis tab.


Don’t forget to check out our daily show Let’s Bet It! on our YouTube channel at https://youtube.com/c/Pickswise at 10:00 am ET.

Mark Zinno and Jared Smith are your hosts today and they will be joined by Tim Murray, @1TimMurray, Co-host of VSiN CFB Betting Podcast to discuss his favorite college football futures bets. Zinno and Jared will also recap Monday Night Football and make their Plays of the Day.

You can also access the show at any time through Spotify and Apple Podcasts (search for Let’s Bet It Presented By Pickswise).

Quote of the Day

”This is my house!

– Vladimir Guerrero Jr. after hitting a walk-off single against the Yankees, snapping New York’s 7-game win streak.

Pickswise is the home of free sports picks, news and best bets. Check out our expert NFL Picks, NBA Picks, MLB Picks and NHL Picks pages for our latest game picks.

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