Wise n' Shine: NFL picks, NBA predictions and World Cup best bets for Monday, November 21

Photo of Phil Agius

Phil Agius


Show Bio

I've been writing about the NFL and a host of other sports for the UK's top daily betting paper the Racing Post for more than 20 years. An incurable Browns fan (1-31 survivor), I also specialise in all kinds of motorsport betting including F1, MotoGP, IndyCar and NASCAR. For Phil Agius media enquiries, please email contact@pickswise.com.
Read more about Phil Agius

Good morning, Pickswise Nation, and welcome to another wonderful week of sports. The NFL plays in Mexico tonight, but before that the USMNT plays its opening World Cup soccer game against Wales. There’s also NBA, NHL and college basketball action today. so let’s get straight to making your next bet better.

About Last Night

Great night of NFL picks
The Pickswise team was in fine form on Sunday’s NFL slate, going 8-3-1 against the spread, 7-5 on over/unders and cashing 3 of our 4 Best Bets. We also hit TWO Same Game Parlays, with a +552 win on the Commanders vs Texans game and an awesome +1600 win on the Raiders vs Broncos matchup. On the field, the Chiefs showed once again that however late opponents pull off apparent game-winning drives against them, it’s probably still too early, with a wild 30-27 win over the Chargers. They now have +470 odds in FanDuel Sportsbook’s Super Bowl market, behind only the Buffalo Bills (+400).

World Cup SGP cashes at +1077 odds!
Our soccer picks for the 2022 World Cup got off to a sensational start as we cashed our Qatar vs Ecuador Same Game Parlay on the opening game of the tournament at +1077 odds. Ecuador comfortably won the game 2-0.

NBA mega parlay was a winner too
Our NBA team was also hot on Sunday, going 6-2 against the spread and cashing our Sunday NBA mega parlay at +645 odds. The Warriors got their 5th win in the last 7 games by beating the Rockets 127-120 and they are almost back to .500 now at 8-9 after their poor start.

2-0 day in the NHL
There were only 2 Sunday games in the NHL, but we found winning bets for both of them as we hit the over in the Blue Jackets’ 5-3 win over the Panthers and the Penguins 3-way ML for their 5-3 win over the Blackhawks, which also cashed our 2-leg parlay at +227 odds.

Top 3 NCAAB teams win
North Carolina, Gonzaga and Houston all won their college basketball games on Sunday, with #2 Gonzaga’s win coming by a score of 88-72 over #4 Kentucky.


Today’s Slate

49ers vs Cardinals in Mexico City
NFL Week 11 comes to a close as the NFL plays a game in its fourth country of the season. After visits to London and Munich, this week’s destination is Mexico City, where the 49ers will take on the Cardinals on Monday Night Football game at 8:15 pm ET on ESPN. Read our 49ers vs Cardinals predictions.

USA takes on Wales in the World Cup
There are 3 World Cup soccer games today as the tournament picks up the pace. The big game sees the United States tackling Wales in Group B at 2:00 pm ET (FS1, Peacock, Telemundo). Read today’s World Cup soccer predictions.

8 NBA games tonight
There’s a solid 8-game NBA slate tonight including 2 games on NBA TV, with Warriors vs Pelicans at 8:00 pm ET and Jazz vs Clippers at 10:30 pm ET. Check out our NBA picks.

Busy night in the NHL
The NHL action continues with a 10-game slate starting at 7:00 pm ET and including a great matchup between the Bruins and Lightning. Read today’s NHL predictions.

There’s college hoops too
The college basketballers are on the courts again today with Texas Tech vs Creighton (2:30 pm ET, ESPN2) among the games on offer. Read today’s NCAAB predictions.

Best Bet of the Day

NBA: Boston Celtics -6 over Chicago Bulls
8:00 pm ET

The hottest team in the NBA heads to Chicago in hopes of getting revenge for an 18-point loss suffered at United Center earlier this season. Boston has won 9 games in a row and has mostly looked untouchable, but tonight they’ll face a proper test against a team they’ve covered against just once in 7 games. The Celtics are most likely getting Marcus Smart back from injury, while Jayson Tatum and Jaylen Brown are red-hot. They are 5-0 SU in their last 5 road games and they’ve beaten Chicago 14 times in the last 20 meetings. Billy Donovan and his Bulls are in a funk. They’ve lost 4 in a row and 6 of their last 7. Check out our full Celtics vs Bulls predictions.


Our Monday Night Football package is stacked with expert analysis and picks. We have a 49ers vs Cardinals Same Game Parlay, MNF prop bets and TD scorer picks. plus Clevta’s SF vs ARZ Best Bets.

For the World Cup, there’s still time to check out our Group B preview and USA team preview and you won’t want to miss our USA vs Wales Same Game Parlay after our success in the opening game of the tournament!

Hockey fans can check out today’s NHL mega parlay and our NHL player props, while for the NBA we have a Warriors vs Pelicans Same Game Parlay and our Monday NBA mega parlay.

Keep an eye out for more great sports analysis as it arrives throughout the day on the Analysis tab.


Don’t forget to check out our daily show Let’s Bet It on our YouTube channel at youtube.com/c/Pickswise at 10:00 am ET.

Jared Smith and Howard Bender are your hosts today and they will be joined by a special guest to discuss the World Cup. Mark Langdon, a walking soccer encyclopedia and head of sports content at the Racing Post in London, will join the show to assess today’s games and give his advice for the rest of the tournament.

The team will also be looking at the winners and losers from the weekend’s NFL action, previewing tonight’s game and assessing the early odds for this week’s college football before revealing their Plays of the Day.

Also, don’t forget to check out the 49ers vs Cardinals preview from this week’s Pickswise Playbook show below!

You can also access the shows at any time through Spotify and Apple Podcasts (search for Let’s Bet It Presented By Pickswise).

Stat of the Day

The 49ers have covered the spread in their last 5 games against NFC West opponents.

Quote of the Day

“On our best day we can beat anyone in the world. Anyone.”

US soccer head coach Gregg Berhalter was in a confident mood in a pre-World Cup interview with ESPN.


Pickswise is the home of free sports picks, news and best bets. Check out our expert NFL Picks, NBA Picks, Soccer Picks and NHL Picks pages for our latest game Picks.

By signing up you agree to our terms and privacy policy