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NFL Week 4 Anytime TD Scorers: Best Picks for Sunday's Games
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NFL Week 4 Anytime TD Scorers: Best Picks for Sunday's Games

Sam Avellone
Sam AvelloneAuthor
UpdatedOct 4, 2026
Reading time4 min

NFL Week 4 continues, as things will kick off early on Sunday with Colts vs Commanders from across the pond in London before a full day of action, headlined by Lions vs Panthers on Sunday Night Football. 

Ahead of Sunday’s slate, I’ve picked out a few of my favorite anytime touchdown bets, all with plus-money odds – including a bonus pick in the London game. Let’s get into the breakdown, and don’t forget our NFL predictions for analysis on sides and totals of every NFL game this season.

NFL Week 4 Anytime Touchdown Scorer: Tyler Warren (IND) +170

Odds courtesy of Fanatics Sportsbook at the time of publishing. Playable to +130. 

The Washington Commanders can’t seem to contain tight ends. While they’re top-half of the league in tight end targets and receptions allowed, they’re bottom-eight in yards and have surrendered the second-most tight-end touchdowns in the league (5). In Week 1, two of Dallas Goedert’s four catches were for touchdowns, and Dallas’ Jake Ferguson scored two more against this defense in Week 2. 

Tyler Warren has been a key part of the Colts passing attack. He’s tied with WR Josh Downs for the most targets, while he leads the team in receptions and receiving touchdowns (2). He has some competition for targets in the red zone, but he should get a few more of those on Sunday considering Keenan Allen won’t play, who leads the team in targets inside the 10-yard line. 

Get our MASSIVE Week 4 NFL parlay at whopping +1917 odds

NFL Week 4 Anytime Touchdown Scorer: Derrick Henry (BAL) 2+ touchdowns +240

Odds courtesy of FanDuel Sportsbook at the time of publishing. Playable to +225. 

I realize betting a player to score twice at odds that you can find other players to score once isn’t exactly the most appealing, but Derrick Henry is simply a different animal. He’s a matchup nightmare week in and week out for opposing defenses, and his workload is among the most secure in the league because of it. In fact, he’s tied at the top of the league in red-zone attempts (18) and red-zone touchdowns (5), while he’s far and away the most used rusher inside the 10 and five-yard lines. 

Henry already has six touchdowns this year, three of which came in Week 1 and two last week. This week, he will go up against his former team in the Tennessee Titans for the first time, which I believe adds some motivation for Henry – even if he doesn’t admit it. Not to mention, the weather in Baltimore projects to be wet, which likely will add to Henry’s workload even more, especially with the Ravens being double-digit favorites at home. Titans QB Cam Ward has been a turnover machine; don’t be surprised to see the Ravens with a couple short-field situations that lead to multiple scoring opportunities for Henry.

Read our full Titans vs Ravens prediction  

NFL Week 4 Anytime Touchdown Scorer: CeeDee Lamb (DAL) +145

Odds courtesy of Fanatics Sportsbook at the time of publishing. Playable to +100. 

CeeDee Lamb to score at nearly +150 in a game with a total in the high-40s? Sign me up. While going against Houston’s defense is daunting, the Texans have been mediocre against the pass, sitting 19th in PPA per pass (SumerSports) and 26th in passing yards allowed per game. Moreover, they’ve allowed five wide-receiver touchdowns this year, which is the second-most in the league behind four teams tied at six.

Lamb has three touchdown grabs this year, but he didn’t have one last week despite being heavily involved in the game plan, bringing in seven of his eight targets for over 110 yards. His heavy involvement in the offense should continue to be a mainstay, especially with Dallas in the underdog role and expected to trail for portions of this game.

Check out our Cowboys vs Texans prediction for this in-state showdown

NFL Week 4 Anytime Touchdown Scorer: Patrick Mahomes (KC) +450

Odds courtesy of Fanatics Sportsbook at the time of publishing. Playable to +400.

Kenneth Walker gets a vast majority of Kansas City’s red-zone work, but Patrick Mahomes, surprisingly, is the one that plays second fiddle with five carries inside the 20-yard line. As Walker continues to dominate, I expect opposing defenses to sell out to stop him more and more, especially in red-zone and goal-line situations, which should open up lanes for Mahomes – who is more mobile than you think. 

Mahomes doesn’t consistently carry the ball, but he’s selective and effective when he does, just like he was in Week 1 when he carried the ball seven times with a score. This Raiders defense has surrendered an average of 7.7 yards per carry on 10 attempts to opposing quarterbacks, so the lanes will likely be there – it’s just a matter of those opportunities being close enough to the end zone for him to cash in on this number. I’m taking my chances on anything better than 4/1. 

Don't miss our NFL expert's best bets for Week 4