Baltimore Orioles vs New York Yankees Prediction, Odds and Picks for Today, 05/01/26

While the New York Yankees had a day off yesterday, the Baltimore Orioles are coming in on a quick turnaround after a doubleheader against the Houston Astros. The Yankees will hand the ball over to Will Warren, who is 3-0 with a 2.59 ERA and a 1.15 WHIP through 6 starts this season. For the Orioles, they’ll send Cade Povich to the mound with a 1-0 record and a 2.19 ERA through 2 games. 

Offensively, the Yankees have been slightly more productive than their counterparts in their last 13 games, posting a .834 OPS and averaging 5.5 runs per game. For Baltimore, they have a .718 OPS and are averaging 5.2 runs per game in that same span. While division games can be tough, the Yankees hold several key advantages here: they have the more proven starter, a slightly better bullpen and a well-rested roster. After the Orioles had to use the majority of their pitching staff in yesterday’s doubleheader, I expect fatigue to be an issue for Baltimore in this one. Look for the Yankees to get things done in the Bronx against their division rivals. 

Orioles vs Yankees prediction: New York Yankees ML (-170) available at time of publishing. Playable to -185.

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