Baltimore Orioles

Baltimore Orioles vs New York Yankees Prediction, Odds and Picks for Today, 05/04/26

Yankee StadiumMASN, YES
Orioles
15-19
Orioles
Today
Yankees
23-11
Yankees

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New York Yankees
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Orioles vs Yankees Pickswise Expert Predictions

Run Line Pick
NY Yankees -1.5(-110)

The New York Yankees will look to complete a 4-game sweep of the Baltimore Orioles on Monday night behind Cam Schlittler, who is 4-1 with a 1.51 ERA and 0.74 WHIP through 7 starts. The Orioles will counter with Shane Baz, who has struggled this season to the tune of a 1-2 record with a 4.50 ERA and 1.50 WHIP across 6 outings. 

The Orioles simply haven’t had answers for New York’s offense in this series, getting outscored 27-9 through the first 3 games. A big part of their offensive success has been from players like Cody Bellinger, Jasson Dominguez, Ben Rice and Aaron Judge. Even with Rice exiting early on Sunday due to a hand injury, he is expected to be available for tonight’s matchup. Baltimore’s struggles go beyond just pitching — it hasn’t been able to generate offense, batting .170 in this series and .196 in the last 7 games. Things won’t get any easier against Schlittler, who has been lights out. On top of that, the Orioles’ bullpen has been heavily utilized throughout the series — while the Yankees come in with a fresher, more reliable relief group. With everything pointing in favor of the Yankees, I’m backing them to win big in the Bronx as they wrap up this AL East matchup against the Orioles.

Orioles vs Yankees prediction: New York -1.5 (-110) available at time of publishing. Playable to -130. 

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Jason Fragomeni

Jason Fragomeni is a MLB sports writer for Pickwise who lives in New York and is a huge fan of the New York Yankees and New York Giants. Jason is a data/statistic fanatic and he’s learned how to apply statistical analyses into the sports betting world. Jason uses data every day to help him determine what picks have the greatest probability of winning, which has helped him when it comes time to make a wager. Jason has been in the sports industry for over 10 years now, and has a wealth of knowledge surrounding sports and is a sports bettor by hobby.
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