HomeMLBMLB PredictionsChicago White Sox vs Cleveland Guardians Prediction, Odds and Picks

Chicago White Sox vs Cleveland Guardians Prediction, Odds and Picks for Saturday, 09/13/25

Updated: 5:00 AM ET Sep 14, 2025

Progressive FieldCHSN

57-91

White Sox

6:10 PM ETSat Sep 13

76-71

Guardians

Javan Shouey

Updated: 5:00 AM ET September 14, 2025

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A lifelong sports fan from Northwestern Pennsylvania. Die-hard supporter of the Steelers, Pirates and Cavaliers. Insane passion for writing about sports and helping others improve. Incredibly thankful for the platform Pickswise is giving me. For Javan Shouey media enquiries, please email contact@pickswise.com.

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