Chicago White Sox vs Los Angeles Angels Prediction, Odds and Picks for Today, 05/05/26

The Chicago White Sox are turning some heads in the American League Central this season, sitting one game below .500 following a 6-0 shutout win over the Los Angeles Angels on Monday evening. The White Sox have won 6 of their last 7 games to climb up the standings, but things haven’t gone as smoothly for the Angels — owning a 1-9 record over their past 10 games. Chicago also has some recent success against Los Angeles, earning a sweep last Monday through Wednesday at Guaranteed Rate Field. The White Sox send Erick Fedde to the mound on Tuesday, with his last start coming against these same Angels — allowing just 5 hits and 2 earned runs over 7.0 innings. Fedde has been solid all season, allowing 3 or fewer earned runs in each of his 6 games (4 starts and 2 following an opener). Despite a 3.24 ERA and several quality starts, the Chicago hitters haven’t been kind to Fedde — tagging him with a 0-3 record due to a lack of run support.

The Angels will send Sam Aldegheri to the mound, who has only pitched 1.2 innings for them this season. Aldegheri is a solid left-handed prospect for Los Angeles, but has been struggling in AAA this season with a 7.77 ERA in five starts with the Salt Lake Bees. He may be struggling in AAA, but it brings a different look for a Chicago offense that doesn’t score a ton of runs. Three of the 4 games between these teams over the last week have produced fewer than 7 runs, and with Fedde’s solid play this season, I think it happens again on Tuesday.

White Sox vs Angels prediction: Under 9 (-110) available at time of publishing. Playable to 8.5.

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