Chicago White Sox vs Los Angeles Angels Prediction, Odds and Picks for Today, 05/06/26

I favor the under on the posted total through 5 innings of play in Wednesday’s matchup between the Los Angeles Angels and the Chicago White Sox. Noah Schultz is the scheduled starter for Chicago as the southpaw hurler is set to make his 5th career MLB start. His first 4 outings have combined for a 2.53 ERA across 21.1 innings of work. Schultz has issued 12 free passes so far, but his batted ball profile is very strong. He ranks 83rd percentile or better in xBA, hard-hit rate, and barrel rate so far this season. Now he faces an Angels lineup that ranks middle of the pack in wOBA against lefties with the 8th highest strikeout rate.

Walbert Urena is set to make his 6th appearance and 4th start of the season for the Angels. Urena is someone who struggles with command of the zone, ranking 4th percentile with his 16.5% walk rate. He is very tough to square up, however, putting together a very strong batted ball profile so far this season. Urena ranks 78th percentile with his 51% ground ball rate, and that allows him to eliminate some of those walks. Chicago is a powerful lineup, but they do hit a bunch of ground balls as well, and this could be a decent spot for Urena to find success after 5 innings of 1-run ball against the Mets in his last start.

White Sox vs Angels prediction: F5 Under 4.5 (-110) available at time of publishing. Playable to -115 odds.