St. Louis Cardinals vs San Diego Padres Prediction, Odds and Picks for Today, 05/09/26

The St. Louis Cardinals delivered a dominant pitching performance last night against the San Diego Padres, holding them to just one hit in a convincing 6-0 victory. Now, the Cardinals will look to keep that momentum rolling as they go for another win on the road. Taking the mound for the Cardinals will be Dustin May who is 3-3 with a 5.15 ERA this season. For the Padres, they’ll counter with Randy Vasquez who is 3-1 with a 3.20 ERA. 

The Padres offense has been a nightmare. In their last 13 games, they’re last in the league in terms of batting average (.212) and are averaging 4.1 runs per game. For the Cardinals, they’re hitting .257 in their last 14 games and are averaging 5 runs per game. Looking at this matchup, I trust the Cardinals to steal another win on the road. Looking at May’s numbers, they look worse than what they are. In his last five starts, he’s 3-1 with a 2.45 ERA with 18 strikeouts. With St. Louis carrying momentum offensively and May finding his rhythm on the mound, the Cardinals will be in another strong position to steal another game on the road, making them my best bet of the day. 

Cardinals vs Padres prediction: Cardinals ML (+125) at the time of publishing. Playable up to +135.