Washington Nationals vs Chicago White Sox Prediction, Odds and Picks for Today, 04/24/26

It has been a bad start to the season for Washington Nationals starting pitcher Miles Mikolas. Things have gotten a bit better since he allowed 11 runs to the Los Angeles Dodgers in the first start of April, including a scoreless outing in his most recent start, but he hasn’t gotten past the 4th inning over his last 3 starts. Mikolas might hold the Chicago White Sox to a couple of runs, but it’s hard to trust the bullpen behind him once he leaves early.

The White Sox will open the game with reliever Bryan Hudson on Friday night. They have utilized the opener at times to get their starting pitchers deeper into games, as their bullpen has been one of the worst in the majors this season. Once Hudson comes out of the game, the plan is for right-hander Erick Fedde to eat a majority of the innings, which is great news for Chicago. Fedde has been getting better every game for the White Sox, and if it wasn’t for some control issues in his most recent start, it could’ve been the best start of the season. Fedde owns a 3.92 ERA, but his xERA is even better at 3.57. Once the opener comes out of the game on Friday, the White Sox have the upper hand.

Nationals vs White Sox prediction: Chicago White Sox ML (-125) available at time of publishing. Playable at that number. 

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