Houston Rockets vs Minnesota Timberwolves Prediction, Odds and Picks for Today, 03/25/26

The Houston Rockets (43-28) and Minnesota Timberwolves (44-28) will engage in an absolutely crucial contest for Western Conference playoff positioning when they collide on Wednesday night in Minnesota. Both teams are in a 3-way battle with Denver for the fourth, fifth and sixth spots, and even the #3 seed is in play. As the standings and the records suggest, this is pretty much an even matchup — and the odds are reflective of that. Home-court advantage could make the difference, so my Rockets vs Timberwolves pick is for Minnesota to win outright.

Anthony Edwards (knee) will miss his fifth consecutive contest for the T-Wolves. The good news is that they are staying afloat without him, boasting a 3-1 record in their last 4 games. This stretch includes a 10-point win over Boston this past Sunday. Ayo Dosunmu (14.5 ppg) has been picking up the slack in a big way. He has scored at least 18 points in 5 straight outings and is averaging 9.0 rebounds and 7.3 assists over the past 3 contests. Meanwhile, Houston is just 18-18 on the road in 2025-26 compared to 25-10 at home. Let’s roll with the ‘Wolves and not bother with the +1.5 spread.

Rockets vs Timberwolves prediction: Minnesota ML (+102) available at time of publishing. Playable to -105.